At the London Centre for Na**tech**logy, a project organized by University College London and Imperial College London, researchers developed **vel na**scale drug delivery vesicles that can be designed to selectively Release only certain cargo.
The vesicles are*polymersomes, tiny bubbles made of a stable polymer, that contain embedded DNA Na**pores within their membranes. The Na**pores are made of self-assembling DNA strings and can be tuned to form into a cylindrical shape having a hole of a predefined size.
The polymersomes can contain organic molecules of various sizes, but only ones that are smaller than the Na**pores will be allowed to exit the containers. Larger enzymes that can be carried along within the vesicles remain catalytically active and so able to take part in nearby*reactions.
The researchers believe the tech**logy has great potential drug delivery, as well as for imaging, biocatalysis, and cell mimicry applications.
08-30-2016, 11:26 PM
Na**vesicles With DNA Na**pores for Selective Release of Therapeutic Compounds
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