Na**vesicles With DNA Na**pores for Selective Release of Therapeutic Compounds
 

Na**vesicles With DNA Na**pores for Selective Release of Therapeutic Compounds
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At the London Centre for Na**tech**logy, a project organized by University College London and Imperial College London, researchers developed **vel na**scale drug delivery vesicles that can be designed to selectively release only certain cargo.

The vesicles are*polymersomes, tiny bubbles made of a stable polymer, that contain embedded DNA na**pores within their membranes. The na**pores are made of self-assembling DNA strings and can be tuned to form into a cylindrical shape having a hole of a predefined size.

The polymersomes can contain organic molecules of various sizes, but only ones that are smaller than the na**pores will be allowed to exit the containers. Larger enzymes that can be carried along within the vesicles remain catalytically active and so able to take part in nearby*reactions.

The researchers believe the tech**logy has great potential drug delivery, as well as for imaging, biocatalysis, and cell mimicry applications.

Study in Angewandte Chemie: Biomimetic Hybrid Na**containers with Selective Permeability…

Via:*London Centre for Na**tech**logy…

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