Portable Holographic Microscope for Diag**sing Gout These days Gout is diag**sed by spotting mo**sodium urate crystals within sy**vial fluid sampled*from patients’ joints. This requires a compensated polarized light Microscope (CPLM), a device large and heavy e**ugh to remain in the hospital laboratory, preventing its use at the point-of-care. Moreover, these types of Microscope have an inherently narrow field-of-view and so make it difficult to see a sample all at once, and so impeding a much easier diag**sis.
UCLA researchers have **w come up with a lens-free polarized Microscope that has both a wide field-of-view and high-resolution, and featuring a color contrast comparable to that of CPLM. It’s cheap and easy to make, light, and can be made Portable for use in different environments.
The Microscope uses lens-free on-chip Holographic imaging that passes light through a polarizer, sample, and then a**ther polarizer before hitting an optical sensor. A computer then processes the data and constructs an*image of what’s under the microscope. The entire image hitting the sensor remains in-focus and at high resolution, providing about 25 square millimeters of field of view, which is about 100 times more than with conventional optical microscopy.