Portable Holographic Microscope for Diag**sing Gout
 

Portable Holographic Microscope for Diag**sing Gout
http://www.medgadget.com/wp-content/...ut-imaging.pngThese days gout is diag**sed by spotting mo**sodium urate crystals within sy**vial fluid sampled*from patients’ joints. This requires a compensated polarized light microscope (CPLM), a device large and heavy e**ugh to remain in the hospital laboratory, preventing its use at the point-of-care. Moreover, these types of microscope have an inherently narrow field-of-view and so make it difficult to see a sample all at once, and so impeding a much easier diag**sis.

http://www.medgadget.com/wp-content/...ical-setup.pngUCLA researchers have **w come up with a lens-free polarized microscope that has both a wide field-of-view and high-resolution, and featuring a color contrast comparable to that of CPLM. It’s cheap and easy to make, light, and can be made portable for use in different environments.

The microscope uses lens-free on-chip holographic imaging that passes light through a polarizer, sample, and then a**ther polarizer before hitting an optical sensor. A computer then processes the data and constructs an*image of what’s under the microscope. The entire image hitting the sensor remains in-focus and at high resolution, providing about 25 square millimeters of field of view, which is about 100 times more than with conventional optical microscopy.

Study in journal*Scientific Reports: Wide-field imaging of birefringent sy**vial fluid crystals using lens-free polarized microscopy for gout diag**sis…

Via:*UCLA…

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