A ?paradigm shift? in the diagnosis of diabetes - كوكو هندية

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قديم 03-03-2018, 09:16 AM
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افتراضي A ?paradigm shift? in the diagnosis of diabetes

PARIS: Scientists on Friday unveiled a revised classification for diabetes, one they said could lead to better treatments and help doctors more accurately predict life-threatening complications from the disease.
There are five distinct types of diabetes that can occur in adulthood, rather than the two currently recognised, they reported in.The findings are consistent with the growing trend toward ?precision medicine,? which takes into account differences between individuals in managing disease. Some 420 million people around the world today suffer from diabetes, with the number expected to rise to 629 million by 2045, according to the International diabetes Federation.
Currently, the disease is divided into two sub-types. With type-1 ? generally diagnosed in childhood and accounting for about 10 percent of cases ? the body simply doesn´t make insulin, a hormone that helps regulate blood sugar levels. For type-2, the body makes some insulin but not enough, which means glucose stays in the blood.
This form of the disease correlates highly with obesity and can, over time, lead to blindness, kidney damage, and heart disease or stroke. Acute cases may also require limb amputations.It has long been known that type-2 diabetes is highly variable, but classification has remained unchanged for decades. For the study, researchers monitored 13,270 newly diagnosed diabetes patients ranging in age from 18 to 97.
By isolating measurements of insulin resistence, insulin secretion, blood sugar levels, age, and the onset of illness, they distinguished five distinct clusters of the disease ? three serious and two milder forms.Among the severe types, a group of patients with insulin resistence ? in which cells are unable to use insulin effectively ? was at far higher risk of kidney disease. ?This group has the most to gain from the new diagnostics as they are the ones who are currently most incorrectly treated,? Groop said.

?paradigm shift? diagnosis diabetes

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