A new study published in December in the Journal of the American Medical Association shows there is no substantial evidence that vitamins and supplements do any significant good. According to Business Insider, the paper reviewed more than 33 studies involving over 50,000 adults over age 50. The researchers wanted to find out if people who took calcium, Vitamin D, or both were less likely to suffer bone fractures. They found that the people on the supplements were no less at risk than the people who didn't take them. While supplements might sound harmless, many are unnecessary, misleading, or even dangerous. The $37-billion-dollar supplement industry is largely unregulated. In the US, no dietary supplements are pre-screened for safety or efficacy.