New Magnetic Na**particles Significantly Improve Hyperthermia for Cancer Treatment
[IMG]http://www.medgadget.com/wp-content/uploads/2015/03/flower-na**particles.jpg[/IMG]Magnetic Na**particles that can be heat up once inside*the body is a promising emerging idea in oncology. A number of such Na**particles have been designed, but their capabilities have been limited. A major issue is being able to target as small an area as possible to be able to destroy just the tumor, leaving nearby healthy tissue mostly untouched. The radiofrequency waves that are beamed*toward the tumor to resonate the Na**particles can damage **rmal cells in the way. That’s why the frequency and strength of the signal has to be kept low, limiting the efficacy of na**particle-induced*hyperthermia..
Researchers at Dartmouth Center of Na**tech**logy Excellence have developed an entire new type of Magnetic Na**particles that are Significantly better at converting RF energy into localized heat than comparable commercially available na**particles. This allows the same strength fields currently being used to attack tumors to be a lot more effective, being able to raise the temperature of the Na**particles much faster while containing the killing effect.
The MNPs consist of small (2–5 nm) single crystals of gamma-Fe2O3 with saccharide chains implanted in their crystalline structure, forming 20–40 nm flower-like aggregates with a hydrodynamic diameter of 110–120 nm. The MNPs form stable (>12 months) colloidal solutions in water and exhibit ** hysteresis under an applied quasistatic Magnetic field, and produce a significant amount of heat at field strengths as low as 100 Oe at 99–164 kHz.
03-04-2015, 03:25 AM
New Magnetic Na**particles Significantly Improve Hyperthermia for Cancer Treatment
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