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03-25-2017, 03:51 PM
New Wirelessly Powered Scalable Retinal Prosthesis
http://www.medgadget.com/wp-content/uploads/2017/03/na**-prosthesis.jpg A collaboration between researchers at University of California San Diego and Na**vision Biosciences, a university spi**ff, has developed a method for constructing wirelessly powered retinal prostheses that interface directly with retinal cells.
http://www.medgadget.com/wp-content/uploads/2017/03/neuron-on-na**wires.jpgPrimary cortical neurons cultured on the surface of an array of optoelectronic na**wires. Here a neuron is pulling the na**wires, indicating the the cell is doing well on this material.
The implant is structured from photosensitive silicon na**wires and, because they produce a textured surface, retinal cells are able to grow on them. Powering the array is a **vel wireless system, that sits on the head near the eye, and provides current to all the na**wires simultaneously. *Changes in light incident onto the na**wires produces a change in the electric signal delivered to cells on the other side of the implant.
The structure of na**wires can be made to be of any size and shape, allowing it to be customized for different ocular anatomies, and the density of the na**wires is much higher than the pixel density of existing retinal prostheses.
The new device was tested in the eyes of lab rats. Here’s a short summary according to UCSD:
For proof-of-concept, the researchers inserted the wirelessly powered na**wire array beneath a transgenic rat retina with rhodopsin P23H k**ck-in retinal degeneration. The degenerated retina interfaced in vitro with a microelectrode array for recording extracellular neural action potentials (electrical “spikes” from neural activity).
The horizontal and bipolar neurons fired action potentials preferentially when the prosthesis was exposed to a combination of light and electrical potential—and were silent when either light or electrical bias was absent, confirming the light-activated and voltage-controlled responsivity of the na**wire array.
Recent flashback:*Artificial Retina Made of Organic Photovoltaic Material Lets Blind Rats See… (http://www.medgadget.com/2017/03/artificial-retina-made-of-organic-photovoltaic-material-lets-blind-rats-see.html)
Study in Journal of Neural Engineering: Towards high-resolution retinal prostheses with direct optical addressing and inductive telemetry… (http://iopscience.iop.org/article/10.1088/1741-2560/13/5/056008/meta)
Via: UCSD… (http://jacobsschool.ucsd.edu/news/news_releases/release.sfe?id=2150)
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http://www.medgadget.com/wp-content/uploads/2017/03/na**-prosthesis.jpg A collaboration between researchers at University of California San Diego and Na**vision Biosciences, a university spi**ff, has developed a method for constructing wirelessly powered retinal prostheses that interface directly with retinal cells.
http://www.medgadget.com/wp-content/uploads/2017/03/neuron-on-na**wires.jpgPrimary cortical neurons cultured on the surface of an array of optoelectronic na**wires. Here a neuron is pulling the na**wires, indicating the the cell is doing well on this material.
The implant is structured from photosensitive silicon na**wires and, because they produce a textured surface, retinal cells are able to grow on them. Powering the array is a **vel wireless system, that sits on the head near the eye, and provides current to all the na**wires simultaneously. *Changes in light incident onto the na**wires produces a change in the electric signal delivered to cells on the other side of the implant.
The structure of na**wires can be made to be of any size and shape, allowing it to be customized for different ocular anatomies, and the density of the na**wires is much higher than the pixel density of existing retinal prostheses.
The new device was tested in the eyes of lab rats. Here’s a short summary according to UCSD:
For proof-of-concept, the researchers inserted the wirelessly powered na**wire array beneath a transgenic rat retina with rhodopsin P23H k**ck-in retinal degeneration. The degenerated retina interfaced in vitro with a microelectrode array for recording extracellular neural action potentials (electrical “spikes” from neural activity).
The horizontal and bipolar neurons fired action potentials preferentially when the prosthesis was exposed to a combination of light and electrical potential—and were silent when either light or electrical bias was absent, confirming the light-activated and voltage-controlled responsivity of the na**wire array.
Recent flashback:*Artificial Retina Made of Organic Photovoltaic Material Lets Blind Rats See… (http://www.medgadget.com/2017/03/artificial-retina-made-of-organic-photovoltaic-material-lets-blind-rats-see.html)
Study in Journal of Neural Engineering: Towards high-resolution retinal prostheses with direct optical addressing and inductive telemetry… (http://iopscience.iop.org/article/10.1088/1741-2560/13/5/056008/meta)
Via: UCSD… (http://jacobsschool.ucsd.edu/news/news_releases/release.sfe?id=2150)
This post New Wirelessly Powered Scalable Retinal Prosthesis (http://www.medgadget.com/2017/03/new-wirelessly-powered-scalable-retinal-prosthesis.html) appeared first on Medgadget (http://www.medgadget.com).
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