rss
08-30-2016, 11:26 PM
Na**vesicles With DNA Na**pores for Selective Release of Therapeutic Compounds
http://www.medgadget.com/wp-content/uploads/2016/08/dna-na**carrier.jpg
At the London Centre for Na**tech**logy, a project organized by University College London and Imperial College London, researchers developed **vel na**scale drug delivery vesicles that can be designed to selectively release only certain cargo.
The vesicles are*polymersomes, tiny bubbles made of a stable polymer, that contain embedded DNA na**pores within their membranes. The na**pores are made of self-assembling DNA strings and can be tuned to form into a cylindrical shape having a hole of a predefined size.
The polymersomes can contain organic molecules of various sizes, but only ones that are smaller than the na**pores will be allowed to exit the containers. Larger enzymes that can be carried along within the vesicles remain catalytically active and so able to take part in nearby*reactions.
The researchers believe the tech**logy has great potential drug delivery, as well as for imaging, biocatalysis, and cell mimicry applications.
Study in Angewandte Chemie: Biomimetic Hybrid Na**containers with Selective Permeability… (http://onlinelibrary.wiley.com/doi/10.1002/anie.201604677/epdf)
Via:*London Centre for Na**tech**logy… (https://www.london-na**.com/research-and-facilities/highlight/dna-based-na**containers-for-drug-delivery)
This post Na**vesicles With DNA Na**pores for Selective Release of Therapeutic Compounds (http://www.medgadget.com/2016/08/na**vesicles-dna-na**pores.html) appeared first on Medgadget (http://www.medgadget.com).
http://feeds.feedburner.com/~ff/Medgadget?d=yIl2AUoC8zA (http://feeds.feedburner.com/~ff/Medgadget?a=PPz92Zqqfz4:gGBv9kKe9lA:yIl2AUoC8zA) http://feeds.feedburner.com/~ff/Medgadget?d=qj6IDK7rITs (http://feeds.feedburner.com/~ff/Medgadget?a=PPz92Zqqfz4:gGBv9kKe9lA:qj6IDK7rITs) http://feeds.feedburner.com/~ff/Medgadget?i=PPz92Zqqfz4:gGBv9kKe9lA:gIN9vFwOqvQ (http://feeds.feedburner.com/~ff/Medgadget?a=PPz92Zqqfz4:gGBv9kKe9lA:gIN9vFwOqvQ)
http://feeds.feedburner.com/~r/Medgadget/~4/PPz92Zqqfz4
http://www.medgadget.com/wp-content/uploads/2016/08/dna-na**carrier.jpg
At the London Centre for Na**tech**logy, a project organized by University College London and Imperial College London, researchers developed **vel na**scale drug delivery vesicles that can be designed to selectively release only certain cargo.
The vesicles are*polymersomes, tiny bubbles made of a stable polymer, that contain embedded DNA na**pores within their membranes. The na**pores are made of self-assembling DNA strings and can be tuned to form into a cylindrical shape having a hole of a predefined size.
The polymersomes can contain organic molecules of various sizes, but only ones that are smaller than the na**pores will be allowed to exit the containers. Larger enzymes that can be carried along within the vesicles remain catalytically active and so able to take part in nearby*reactions.
The researchers believe the tech**logy has great potential drug delivery, as well as for imaging, biocatalysis, and cell mimicry applications.
Study in Angewandte Chemie: Biomimetic Hybrid Na**containers with Selective Permeability… (http://onlinelibrary.wiley.com/doi/10.1002/anie.201604677/epdf)
Via:*London Centre for Na**tech**logy… (https://www.london-na**.com/research-and-facilities/highlight/dna-based-na**containers-for-drug-delivery)
This post Na**vesicles With DNA Na**pores for Selective Release of Therapeutic Compounds (http://www.medgadget.com/2016/08/na**vesicles-dna-na**pores.html) appeared first on Medgadget (http://www.medgadget.com).
http://feeds.feedburner.com/~ff/Medgadget?d=yIl2AUoC8zA (http://feeds.feedburner.com/~ff/Medgadget?a=PPz92Zqqfz4:gGBv9kKe9lA:yIl2AUoC8zA) http://feeds.feedburner.com/~ff/Medgadget?d=qj6IDK7rITs (http://feeds.feedburner.com/~ff/Medgadget?a=PPz92Zqqfz4:gGBv9kKe9lA:qj6IDK7rITs) http://feeds.feedburner.com/~ff/Medgadget?i=PPz92Zqqfz4:gGBv9kKe9lA:gIN9vFwOqvQ (http://feeds.feedburner.com/~ff/Medgadget?a=PPz92Zqqfz4:gGBv9kKe9lA:gIN9vFwOqvQ)
http://feeds.feedburner.com/~r/Medgadget/~4/PPz92Zqqfz4