Our hearts evolved to pump blood in a pulsing manner. The Heartbeat that nearly the entire body experiences may be important for a variety of biological processes, but laboratory experiments are **rmally performed without accounting for this factor. **w researchers at the University of Michigan have developed a microfluidic chip that uses gravity and pressure differences to simulate a pulsating microenvironment within which tests can be performed.
The chip costs pennies to produce, consisting of **thing but carefully produced*lithographed silicon rubber. The device can be preloaded to be fed by a specific mix of cells, compounds, and corresponding media, and left to pump them through for hours to get a perspective of what effect pulsed rhythms have on different processes.
Here’s a U of M video with Shuichi Takayama, the lead researcher on the project: