Contrast Agents are used in medicine to*help visualize things*that certain imaging modalities, such as MR or CT, can**t resolve on their own. Typically, each modality has its own imaging Agents that don’t help when switching to a**ther imaging system.*To help overcome this limitation, researchers at MIT developed na**particles that, depending on the situation, either fluoresce or*are visible Under MRI.
The particles are a new variety of so-called branched-bottlebrush polymer dual-modality organic radical Contrast agents. They are nitroxide radical-based na**structures that are excitable by Near-Infrared light and are readily identified Under MRI. The team used the particles to follow the path of vitamin C spreading throughout the bodies of mice. High levels of vitamin C make the particles hard to see Under MRI, but they’re readily apparent when illuminated with near-infrared. The opposite holds true at lower concentrations of vitamin C, so MRI is used to track it in that instance.
11-18-2014, 10:31 PM
Dual-Imaging Contrast Agents Work Under MRI, Near-Infrared
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