Blackheads are annoying for everyone, and it can be difficult to get rid of. According to dermatologists, there are a few things that work to remove the pesky spots. One option is to Leave a salicylic acid gel on the blackheads, since it?s good for dissolving them. another is to try a retinoid, and there are low-strength retinoids for those with sensitive skin. Another choice is to Use an enzymatic exfoliator at least twice a week.