Adoptive immu**therapy is a technique that can help fight tumors by training large numbers of T cells to attack the particular cancer*cells present in a patient. This can be a difficult process because a large number of Cell-Cell Interactions have to be monitored in order to spot the immune cells that are creating the wanted*reactions. A collaboration between*University of Houston and the University of Texas M.D. Anderson Cancer Center has led to the development of a new System that can screen large numbers of immune effector cells*interacting with tumor cells.
The System called TIMING, for*Time-lapse Imaging Microscopy in Na**well Grids, can go through tens of thousands of cell Interactions and can be adapted for applications outside of immu**therapy, essentially wherever tracking of biological cells in large quantities is important to find a needle in a haystack.
TIMING works thanks to tiny wells within which pairs of cells spend quality time*close together. A microscope camera films thousands of these wells, essentially at the same time, while a supercomputer is used to analyze the videos for visual changes.
08-10-2015, 11:25 PM
Personalized Immu**therapy: New System Boosts Analysis of Cell-Cell Interactions
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