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02-26-2015, 03:01 AM
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New Method for Creating Optimal Drug Combinations
[IMG]http://www.medgadget.com/wp-content/uploads/2015/02/combo-na**-drug.jpg[/IMG]Optimization of na**medicine combination therapy. Schematic of a combination therapy based on na**diamond-drug complexes for breast cancer treatment, left. The tech**logy platform constructs a personalized response map that pinpoints the Optimal drug-dose ratio, right. Combination therapies, particularly in cancer treatment, are a popular way of attacking aggressive diseases, but they often miss their targets. Genetic data is typically used as a guide for targeting, but genes mutate and tumors can consist of different strains. **w researchers at UCLA have developed a new technique for Creating patient specific combination Drug regimens that, at least in laboratory tests, have shown more effective than existing techniques. Moreover, to make the Drug therapy even more powerful, the team used na**diamonds in helping to deliver ***** to neoplastic cells. Instead of focusing on genetics, the so-called Feedback System Control.II uses phe**typic information in evaluating the effectiveness of a particular Drug combination. Once the Optimal combo therapy has been identified, the ***** are assembled along with na**diamonds attached to their surface. The compounds were introduced to cancer cell lines and the the na**diamonds acted as anchors that prevented the ***** from being excreted by the cancer cells. This allowed the Drug therapy to act for longer periods of time, getting the most out of each Drug payload without harming as many healthy cells nearby. “This optimized na**drug combination approach can be used for virtually every type of disease model and is certainly **t limited to cancer,” said Dr. Chih-Ming Ho, a professor of mechanical engineering at UCLA *“Additionally, this study shows that we can design optimized Combinations for virtually every type of Drug and any type of na**therapy.” Study in ACS Na**:*Mechanism-Independent Optimization of Combinatorial Na**diamond and Unmodified Drug Delivery Using a Phe**typically Driven Platform Tech**logy More from UCLA: Cutting-edge tech**logy optimizes cancer therapy with na**medicine drug combinations… The post New Method for Creating Optimal Drug Combinations appeared first on Medgadget. ??????? ??????: New Method for Creating Optimal Drug Combinations || ??????: rss || ??????: اسم منتداك
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