Laboratory
Blood Vessel to
Study How
Cancers Spread
The mechanisms by which
Cancers metastasize and propagate throughout the body remain mostly a mystery. Primary tumors can be found and *******, but all too frequently the
Cancers randomly recur to fight a**ther fight. To better understand how cancer cells break off and travel through the
Blood stream to colonize other parts of the body, researchers at Johns Hopkins University created a transparent artificial
Blood Vessel in which cancer behavior can be studied close-up.
The
Vessel is coated with collagen and seeded with endothelial cells. Once the device is ready, a clump of breast tumor tissue tagged with fluorescent markers is placed just outside the collagen matrix. Using a microscope, the markers can be tracked as the cancer cells move through the artificial
Vessel wall to reach the
Blood flow within the lumen.
The Johns Hopkins Institute for Na**BioTech**logy released a podcast about this research which you can listen to*
here…
Johns Hopkins:*
Artificial blood vessel visualizes cancer cell journey…
Study in journal
Cancer Research:*
Live-Cell Imaging of Invasion and Intravasation in an Artificial Microvessel Platform…
