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Gene editing rescues hearing of mice
PARIS: Genetically destined for deafness, ?Beethoven? lab mice had their hearing rescued by a gene editing technique that holds promise for humans with the same hereditary fate, ?excited? scientists said Wednesday. By injecting a gene ?editor? directly into the sound-sensing ear cells of newborn rodents bred with deafness-causing DNA, scientists ?disabled? the mutant gene that would have robbed them of hearing over time. At the age of four weeks, uninjected mice were unable to hear sound at 80 decibels on the loudness scale ? about the level of city traffic. Treated mice, however, reacted to sound at a much lower 65 decibels ? the level of normal human conversation ? a team of scientists in the United States and China wrote in the science journal Nature.
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