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06-17-2014, 08:50 PM
Injectable Na**construct Particles to Turn MRI Scanners Into Cancer Killers
http://cdn.medgadget.com/wp-content/uploads/2014/06/MRI-particles-for-tumor-detection.jpgSilicon mesoporous particles, aka SiMPS, about 1,000 na**meters across contain thousands of much smaller particles of iron oxide. The SiMPs can be manipulated by magnets and gather at the site of tumors, where they can be heated to kill malignant tumors or trigger the release of *****. Courtesy of the Wilson Group
Magnetic resonance imaging (MRI) is regularly used to spot cancer tumors deep within the body, but therapy to fight them is delivered in a completely different fashion, whether it be surgery, chemo, or radiation. A special composite microparticle designed by an international team of researchers may turn MRI itself into a therapeutic modality.
The team , led by*scientists from Rice University and The Methodist Hospital Research Institute (TMHRI), have developed silicon mesoporous*particles (SiMPS) that have a bunch of iron oxide na**particles embedded within. The iron oxide is readily visible under MRI and allows the particles to be guided to move to specific spots within the body using the scanner’s magnetic field. Once the particles have been delivered to a tumor, they can be made to heat up, yet again using MRI’s magnets, killing tumors. All this is yet in a pre-clinical stage and remains to be further developed for use on human patients, but the tech**logy is striking in its elegance and potential to revolutionize treatment of a variety of cancers.
Study in Advanced Functional Materials: Hierarchically Structured Magnetic Na**constructs with Enhanced Relaxivity and Cooperative Tumor Accumulation… (http://onlinelibrary.wiley.com/doi/10.1002/adfm.201400653/abstract)
More from Rice: Rice, Methodist researchers merge magnetic particles to detect, fight disease… (http://news.rice.edu/2014/06/13/na**scale-composites-improve-mri-2/)
http://feeds.feedburner.com/~ff/Medgadget?d=yIl2AUoC8zA (http://feeds.feedburner.com/~ff/Medgadget?a=G9rchyWjoLc:ht7c6BDeWWE:yIl2AUoC8zA) http://feeds.feedburner.com/~ff/Medgadget?d=qj6IDK7rITs (http://feeds.feedburner.com/~ff/Medgadget?a=G9rchyWjoLc:ht7c6BDeWWE:qj6IDK7rITs) http://feeds.feedburner.com/~ff/Medgadget?i=G9rchyWjoLc:ht7c6BDeWWE:gIN9vFwOqvQ (http://feeds.feedburner.com/~ff/Medgadget?a=G9rchyWjoLc:ht7c6BDeWWE:gIN9vFwOqvQ)
http://feeds.feedburner.com/~r/Medgadget/~4/G9rchyWjoLc
http://cdn.medgadget.com/wp-content/uploads/2014/06/MRI-particles-for-tumor-detection.jpgSilicon mesoporous particles, aka SiMPS, about 1,000 na**meters across contain thousands of much smaller particles of iron oxide. The SiMPs can be manipulated by magnets and gather at the site of tumors, where they can be heated to kill malignant tumors or trigger the release of *****. Courtesy of the Wilson Group
Magnetic resonance imaging (MRI) is regularly used to spot cancer tumors deep within the body, but therapy to fight them is delivered in a completely different fashion, whether it be surgery, chemo, or radiation. A special composite microparticle designed by an international team of researchers may turn MRI itself into a therapeutic modality.
The team , led by*scientists from Rice University and The Methodist Hospital Research Institute (TMHRI), have developed silicon mesoporous*particles (SiMPS) that have a bunch of iron oxide na**particles embedded within. The iron oxide is readily visible under MRI and allows the particles to be guided to move to specific spots within the body using the scanner’s magnetic field. Once the particles have been delivered to a tumor, they can be made to heat up, yet again using MRI’s magnets, killing tumors. All this is yet in a pre-clinical stage and remains to be further developed for use on human patients, but the tech**logy is striking in its elegance and potential to revolutionize treatment of a variety of cancers.
Study in Advanced Functional Materials: Hierarchically Structured Magnetic Na**constructs with Enhanced Relaxivity and Cooperative Tumor Accumulation… (http://onlinelibrary.wiley.com/doi/10.1002/adfm.201400653/abstract)
More from Rice: Rice, Methodist researchers merge magnetic particles to detect, fight disease… (http://news.rice.edu/2014/06/13/na**scale-composites-improve-mri-2/)
http://feeds.feedburner.com/~ff/Medgadget?d=yIl2AUoC8zA (http://feeds.feedburner.com/~ff/Medgadget?a=G9rchyWjoLc:ht7c6BDeWWE:yIl2AUoC8zA) http://feeds.feedburner.com/~ff/Medgadget?d=qj6IDK7rITs (http://feeds.feedburner.com/~ff/Medgadget?a=G9rchyWjoLc:ht7c6BDeWWE:qj6IDK7rITs) http://feeds.feedburner.com/~ff/Medgadget?i=G9rchyWjoLc:ht7c6BDeWWE:gIN9vFwOqvQ (http://feeds.feedburner.com/~ff/Medgadget?a=G9rchyWjoLc:ht7c6BDeWWE:gIN9vFwOqvQ)
http://feeds.feedburner.com/~r/Medgadget/~4/G9rchyWjoLc