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07-15-2017, 03:43 AM
High Speed Automated Whole Brain Slicing and Imaging System Revealed in Japan
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AT Osaka University in Japan researchers have developed a new high speed system that slices and images brains significantly faster than previous approaches. These days it can take up to a week to slice, stain, image, and reconstruct brains in lab studies at a subcellular resolution. The number of slices is astounding, but by automating the process, the new block-face ****** microscopy tomography (FAST) system can image the whole brain in less than two and a half hours.
The setup consists of a spinning confocal microscope and slicer, as well as a staining mechanism that work together in unison to systematically go through the brain slice by slice. It works on larger brains as well, as the researchers tested it on a brain of a marmoset, a New World monkey, and human brains as well, achieving the same level of precision, but of course taking more time than with a mouse brain.
The new device should certainly help neuroscientists to construct **vel*experiments that will answer many questions currently hidden due to limits of contemporary tech**logy.
Study in journal Neuron: High-Speed and Scalable Whole-Brain Imaging in Rodents and Primates… (http://www.cell.com/neuron/abstract/S0896-6273(17)30455-5)
Via: Osaka University… (http://www.alphagalileo.org/ViewItem.aspx?ItemId=177190&CultureCode=en)
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https://www.medgadget.com/wp-content/uploads/2017/07/fast-featured-300x213.jpghttps://www.medgadget.com/wp-content/uploads/2017/07/FAST-setup.png
AT Osaka University in Japan researchers have developed a new high speed system that slices and images brains significantly faster than previous approaches. These days it can take up to a week to slice, stain, image, and reconstruct brains in lab studies at a subcellular resolution. The number of slices is astounding, but by automating the process, the new block-face ****** microscopy tomography (FAST) system can image the whole brain in less than two and a half hours.
The setup consists of a spinning confocal microscope and slicer, as well as a staining mechanism that work together in unison to systematically go through the brain slice by slice. It works on larger brains as well, as the researchers tested it on a brain of a marmoset, a New World monkey, and human brains as well, achieving the same level of precision, but of course taking more time than with a mouse brain.
The new device should certainly help neuroscientists to construct **vel*experiments that will answer many questions currently hidden due to limits of contemporary tech**logy.
Study in journal Neuron: High-Speed and Scalable Whole-Brain Imaging in Rodents and Primates… (http://www.cell.com/neuron/abstract/S0896-6273(17)30455-5)
Via: Osaka University… (http://www.alphagalileo.org/ViewItem.aspx?ItemId=177190&CultureCode=en)
http://feeds.feedburner.com/~ff/Medgadget?d=yIl2AUoC8zA (http://feeds.feedburner.com/~ff/Medgadget?a=cO_XN8Gv5YU:yai9gQDncSE:yIl2AUoC8zA) http://feeds.feedburner.com/~ff/Medgadget?d=qj6IDK7rITs (http://feeds.feedburner.com/~ff/Medgadget?a=cO_XN8Gv5YU:yai9gQDncSE:qj6IDK7rITs) http://feeds.feedburner.com/~ff/Medgadget?i=cO_XN8Gv5YU:yai9gQDncSE:gIN9vFwOqvQ (http://feeds.feedburner.com/~ff/Medgadget?a=cO_XN8Gv5YU:yai9gQDncSE:gIN9vFwOqvQ)
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