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06-29-2017, 10:12 PM
Hand-Held Probe Can Detect Cancer Cells in Real-Time During Surgery
https://www.medgadget.com/wp-content/uploads/2017/06/brain-probe-dd-1-300x238.jpghttps://www.medgadget.com/wp-content/uploads/2017/06/brain-probe-in-action.jpgScientists in Montreal, Canada have perfected a hand-held Raman spectroscopy probe that surgeons can use to distinguish between cancer cells and **rmal tissue.
Raman spectroscopy is a technique that involves shining light on a material and analyzing how it scatters. Scientists have usedآ*the method for years to analyze and characterize living tissues and cells. This probe is the latest iteration of a Raman device this research team first developed in 2015 (https://www.medgadget.com/2015/02/spectroscopy-probe-improve-intraop-brain-cancer-detection-video.html). They have **w perfected the design, and the new device has improved accuracy and is highly specific. It can reportedly detect brain, lung, colon and skin cancer cells, with almost 100% sensitivity.
In practical terms, a surgeon can point the probe at a suspect tissue during surgery and see if it contains any cancerous cells. This could be a game changer, as sometimes tumors are very difficult to distinguish from healthy tissue. â??Minimizing, or completely eliminating, the number of cancer cells during surgery is a critical part of cancer treatment, yet detecting cancer cells during surgery is challenging,â?* explains Dr. Kevin Petrecca, a neurosurgical oncology specialist, and author on the recent study published in Cancer Research. â??Often it is impossible to visually distinguish cancer from **rmal brain, so invasive brain cancer cells frequently remain after surgery, leading to cancer recurrence and a worse prog**sis. Surgically minimizing the number of cancer cells improves patient outcomes.â?*
The new probe incorporates fluorescence spectroscopy to analyze the metabolic composition of the cells. The first probe is currently being tested in a large-scale clinical trial on patients with brain tumors. However, in a smaller trial, the new probe demonstrated a 10% increase in cancer detection sensitivity compared with the older design.
https://www.medgadget.com/wp-content/uploads/2017/06/brain-probe.jpgSchematic depiction of the probe being used to interrogate brain tissue during surgery. The image shows a photograph of the probe held by a surgeon, Raman spectral associated with **rmal brain and cancer, as well as a magnetic resonance image (MRI) of a brain cancer patient with the red area representing the tumor.
Flashback:آ*Spectroscopy Probe to Improve Intraop Brain Cancer Detection… (https://www.medgadget.com/2015/02/spectroscopy-probe-improve-intraop-brain-cancer-detection-video.html)
Study in Cancer Research: Highly accurate detection of cancer in situ with intraoperative, label-free, multimodal optical spectroscopy… (http://dx.doi.org/10.1158/0008-5472.CAN-17-0668)
Via: Polytechnique Montrأ©al… (http://www.polymtl.ca/salle-de-presse/en/newsreleases/infallible-hand-held-probe-aid-cancer-surgery)
http://feeds.feedburner.com/~ff/Medgadget?d=yIl2AUoC8zA (http://feeds.feedburner.com/~ff/Medgadget?a=sA6rnKd2Yxc:0L1kqTRIOWk:yIl2AUoC8zA) http://feeds.feedburner.com/~ff/Medgadget?d=qj6IDK7rITs (http://feeds.feedburner.com/~ff/Medgadget?a=sA6rnKd2Yxc:0L1kqTRIOWk:qj6IDK7rITs) http://feeds.feedburner.com/~ff/Medgadget?i=sA6rnKd2Yxc:0L1kqTRIOWk:gIN9vFwOqvQ (http://feeds.feedburner.com/~ff/Medgadget?a=sA6rnKd2Yxc:0L1kqTRIOWk:gIN9vFwOqvQ)
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https://www.medgadget.com/wp-content/uploads/2017/06/brain-probe-dd-1-300x238.jpghttps://www.medgadget.com/wp-content/uploads/2017/06/brain-probe-in-action.jpgScientists in Montreal, Canada have perfected a hand-held Raman spectroscopy probe that surgeons can use to distinguish between cancer cells and **rmal tissue.
Raman spectroscopy is a technique that involves shining light on a material and analyzing how it scatters. Scientists have usedآ*the method for years to analyze and characterize living tissues and cells. This probe is the latest iteration of a Raman device this research team first developed in 2015 (https://www.medgadget.com/2015/02/spectroscopy-probe-improve-intraop-brain-cancer-detection-video.html). They have **w perfected the design, and the new device has improved accuracy and is highly specific. It can reportedly detect brain, lung, colon and skin cancer cells, with almost 100% sensitivity.
In practical terms, a surgeon can point the probe at a suspect tissue during surgery and see if it contains any cancerous cells. This could be a game changer, as sometimes tumors are very difficult to distinguish from healthy tissue. â??Minimizing, or completely eliminating, the number of cancer cells during surgery is a critical part of cancer treatment, yet detecting cancer cells during surgery is challenging,â?* explains Dr. Kevin Petrecca, a neurosurgical oncology specialist, and author on the recent study published in Cancer Research. â??Often it is impossible to visually distinguish cancer from **rmal brain, so invasive brain cancer cells frequently remain after surgery, leading to cancer recurrence and a worse prog**sis. Surgically minimizing the number of cancer cells improves patient outcomes.â?*
The new probe incorporates fluorescence spectroscopy to analyze the metabolic composition of the cells. The first probe is currently being tested in a large-scale clinical trial on patients with brain tumors. However, in a smaller trial, the new probe demonstrated a 10% increase in cancer detection sensitivity compared with the older design.
https://www.medgadget.com/wp-content/uploads/2017/06/brain-probe.jpgSchematic depiction of the probe being used to interrogate brain tissue during surgery. The image shows a photograph of the probe held by a surgeon, Raman spectral associated with **rmal brain and cancer, as well as a magnetic resonance image (MRI) of a brain cancer patient with the red area representing the tumor.
Flashback:آ*Spectroscopy Probe to Improve Intraop Brain Cancer Detection… (https://www.medgadget.com/2015/02/spectroscopy-probe-improve-intraop-brain-cancer-detection-video.html)
Study in Cancer Research: Highly accurate detection of cancer in situ with intraoperative, label-free, multimodal optical spectroscopy… (http://dx.doi.org/10.1158/0008-5472.CAN-17-0668)
Via: Polytechnique Montrأ©al… (http://www.polymtl.ca/salle-de-presse/en/newsreleases/infallible-hand-held-probe-aid-cancer-surgery)
http://feeds.feedburner.com/~ff/Medgadget?d=yIl2AUoC8zA (http://feeds.feedburner.com/~ff/Medgadget?a=sA6rnKd2Yxc:0L1kqTRIOWk:yIl2AUoC8zA) http://feeds.feedburner.com/~ff/Medgadget?d=qj6IDK7rITs (http://feeds.feedburner.com/~ff/Medgadget?a=sA6rnKd2Yxc:0L1kqTRIOWk:qj6IDK7rITs) http://feeds.feedburner.com/~ff/Medgadget?i=sA6rnKd2Yxc:0L1kqTRIOWk:gIN9vFwOqvQ (http://feeds.feedburner.com/~ff/Medgadget?a=sA6rnKd2Yxc:0L1kqTRIOWk:gIN9vFwOqvQ)
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