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مشاهدة النسخة كاملة : Skin ***** Automatically Releases Insulin to Control Blood Sugar


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01-20-2017, 06:44 PM
Skin ***** Automatically Releases Insulin to Control Blood Sugar
http://www.medgadget.com/wp-content/uploads/2017/01/insulin-delivery-*****.jpg

A collaboration between scientists at*University of **rth Carolina at Chapel Hill, **rth Carolina State University, and*Changchun Institute of Applied Chemistry at the*Chinese Academy of Sciences has developed a **vel skin ***** that delivers insulin in response to high levels of measured glucose. The tech**logy, if proven to work successfully in humans, may have a transformative effect on diabetes management.

The ***** has a bunch of microneedles that are sensitive to glucose, breaking up when a high concentration of the sugar is detected. The needles are hollow and each contains a small dose of insulin that is released when the needles degrade.

The needles are made from a peroxide-reacting polymer that is loaded with glucose oxidase. When the glucose oxidase reacts with glucose, H2O2 is produced and the needles disintegrate and release their cargo of insulin.

The ***** was trialed on lab mice who underwent spikes in glucose levels. The ***** successfully controlled those and reduced the blood glucose levels to **rmal within two hours of a glucose spike.

Study in ACS Na**:*H2O2-Responsive Vesicles Integrated with Transcutaneous *****es for Glucose-Mediated Insulin Delivery… (http://pubs.acs.org/doi/abs/10.1021/acsna**.6b06892)

Via: American Chemical Society… (https://www.acs.org/content/acs/en/pressroom/presspacs/2017/acs-presspac-january-18-2017/toward-a-smart-*****-that-automatically-delivers-insulin-when-needed.html)

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