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09-01-2016, 07:31 PM
Drug Eluting Contact Lenses Treat Glaucoma
http://www.medgadget.com/wp-content/uploads/2016/08/new-contact-lens.jpghttp://www.medgadget.com/wp-content/uploads/2016/08/eluting-contact-lens.jpg
Lata**prost (Xalatan) pressure reducing eye drops are the first line of defense against glaucoma. They’re unpleasant e**ugh for a lot of patients to the point that the burning effect leads to poor adherence. What if there were contact lenses that release the drug slowly right onto the eyeball in a precise amount? Well, researchers at*Boston Children’s Hospital and*Massachusetts Eye and Ear have been successfully testing just such devices on monkeys with glaucoma in one eye.
Published in journal*Ophthalmology, the team describes the creation of high and low dose contact lenses using*lata**prost-polymer film. The film was placed within a hydrogel and the resulting material coated onto a contact lens.
Trying the lenses on the monkeys, the researchers showed that the low dose version was as effective as daily lata**prost eye drops and the high dose version was even better than the drops at reducing intraocular pressure.
The researchers are looking forward to the next steps of identifying the optimal dosage that keeps side effects low while optimizing therapy, potentially leading to the introduction of these devices into clinical practice in the coming years.
Study in journal*Ophthalmology: Lata**prost-Eluting Contact Lenses in Glaucomatous Monkeys… (http://www.aaojournal.org/article/S0161-6420%2816%2930506-1/fulltext)
This post Drug Eluting Contact Lenses Treat Glaucoma (http://www.medgadget.com/2016/09/drug-eluting-contact-lenses-treat-glaucoma.html) appeared first on Medgadget (http://www.medgadget.com).
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http://www.medgadget.com/wp-content/uploads/2016/08/new-contact-lens.jpghttp://www.medgadget.com/wp-content/uploads/2016/08/eluting-contact-lens.jpg
Lata**prost (Xalatan) pressure reducing eye drops are the first line of defense against glaucoma. They’re unpleasant e**ugh for a lot of patients to the point that the burning effect leads to poor adherence. What if there were contact lenses that release the drug slowly right onto the eyeball in a precise amount? Well, researchers at*Boston Children’s Hospital and*Massachusetts Eye and Ear have been successfully testing just such devices on monkeys with glaucoma in one eye.
Published in journal*Ophthalmology, the team describes the creation of high and low dose contact lenses using*lata**prost-polymer film. The film was placed within a hydrogel and the resulting material coated onto a contact lens.
Trying the lenses on the monkeys, the researchers showed that the low dose version was as effective as daily lata**prost eye drops and the high dose version was even better than the drops at reducing intraocular pressure.
The researchers are looking forward to the next steps of identifying the optimal dosage that keeps side effects low while optimizing therapy, potentially leading to the introduction of these devices into clinical practice in the coming years.
Study in journal*Ophthalmology: Lata**prost-Eluting Contact Lenses in Glaucomatous Monkeys… (http://www.aaojournal.org/article/S0161-6420%2816%2930506-1/fulltext)
This post Drug Eluting Contact Lenses Treat Glaucoma (http://www.medgadget.com/2016/09/drug-eluting-contact-lenses-treat-glaucoma.html) appeared first on Medgadget (http://www.medgadget.com).
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