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04-16-2016, 02:19 PM
**vel Na**tower Electrodes for Deep Tissue Intracellular Recordings
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Electrophysiology is an invaluable technique for studying the electrical activity of neurons in the brain and has important clinical applications. The use of na**wire and na**tube intracellular electrode recording devices has improved the spatial resolution and sensitivity of electrophysiological techniques. However, intracellular recordings within thick tissues is limited by the length of the na**tube/na**wire electrode, which has insufficient stiffness at lengths greater than 10 µm. As a result, existing na**devices can**t be used to record neuronal electrical activity within thick tissue slices ex vivo or within deep tissue structures in vivo.
To overcome this challenge, researchers at Toyohashi University of Tech**logy in Japan have developed a long na**scale-tipped microneedle electrode.* The 120 µm-long “na**tower” electrode is sufficiently strong to penetrate thicker and deeper tissue structures, overcoming the limitations of conventional na**tube and na**wire electrodes.* The development of this device, described in an article published in Small, diversifies the scope of preclinical and clinical applications of na**electrodes in electrophysiology.
Study in Small: Na**scale-Tipped High-Aspect-Ratio Vertical Microneedle Electrodes for Intracellular Recordings (http://onlinelibrary.wiley.com/doi/10.1002/smll.201600172/abstract?systemMessage=Subscribe+and+renew+is+curr ently+unavailable+online.+Please+contact+customer+ care+to+place+an+order:++http://olabout.wiley.com/WileyCDA/Section/id-397203.html++.Apologies+for+the+inconvenience.)
Via:*Toyohashi University of Tech**logy (https://hameed.nwar.uk/vb/chrome-extension://mhjfbmdgcfjbbpaeojofohoefgiehjai/index.html)
The post **vel Na**tower Electrodes for Deep Tissue Intracellular Recordings (http://www.medgadget.com/2016/04/**vel-na**tower-electrodes-deep-tissue-intracellular-recordings.html) appeared first on Medgadget (http://www.medgadget.com).
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http://www.medgadget.com/wp-content/uploads/2016/04/na**towers.jpg (http://www.medgadget.com/wp-content/uploads/2016/04/na**towers.jpg)
Electrophysiology is an invaluable technique for studying the electrical activity of neurons in the brain and has important clinical applications. The use of na**wire and na**tube intracellular electrode recording devices has improved the spatial resolution and sensitivity of electrophysiological techniques. However, intracellular recordings within thick tissues is limited by the length of the na**tube/na**wire electrode, which has insufficient stiffness at lengths greater than 10 µm. As a result, existing na**devices can**t be used to record neuronal electrical activity within thick tissue slices ex vivo or within deep tissue structures in vivo.
To overcome this challenge, researchers at Toyohashi University of Tech**logy in Japan have developed a long na**scale-tipped microneedle electrode.* The 120 µm-long “na**tower” electrode is sufficiently strong to penetrate thicker and deeper tissue structures, overcoming the limitations of conventional na**tube and na**wire electrodes.* The development of this device, described in an article published in Small, diversifies the scope of preclinical and clinical applications of na**electrodes in electrophysiology.
Study in Small: Na**scale-Tipped High-Aspect-Ratio Vertical Microneedle Electrodes for Intracellular Recordings (http://onlinelibrary.wiley.com/doi/10.1002/smll.201600172/abstract?systemMessage=Subscribe+and+renew+is+curr ently+unavailable+online.+Please+contact+customer+ care+to+place+an+order:++http://olabout.wiley.com/WileyCDA/Section/id-397203.html++.Apologies+for+the+inconvenience.)
Via:*Toyohashi University of Tech**logy (https://hameed.nwar.uk/vb/chrome-extension://mhjfbmdgcfjbbpaeojofohoefgiehjai/index.html)
The post **vel Na**tower Electrodes for Deep Tissue Intracellular Recordings (http://www.medgadget.com/2016/04/**vel-na**tower-electrodes-deep-tissue-intracellular-recordings.html) appeared first on Medgadget (http://www.medgadget.com).
http://feeds.feedburner.com/~ff/Medgadget?d=yIl2AUoC8zA (http://feeds.feedburner.com/~ff/Medgadget?a=po1Y6LUS33g:Kle1eqsJHN8:yIl2AUoC8zA) http://feeds.feedburner.com/~ff/Medgadget?d=qj6IDK7rITs (http://feeds.feedburner.com/~ff/Medgadget?a=po1Y6LUS33g:Kle1eqsJHN8:qj6IDK7rITs) http://feeds.feedburner.com/~ff/Medgadget?i=po1Y6LUS33g:Kle1eqsJHN8:gIN9vFwOqvQ (http://feeds.feedburner.com/~ff/Medgadget?a=po1Y6LUS33g:Kle1eqsJHN8:gIN9vFwOqvQ)
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