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مشاهدة النسخة كاملة : Cheap, Portable, Multiplexed Device Detects Ultra-low Concentrations of Diag**stic Bi


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02-23-2016, 08:44 PM
Cheap, Portable, Multiplexed Device Detects Ultra-low Concentrations of Diag**stic Biomarkers
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At the*´Ecole Polytechnique Fédérale de Lausanne, Switzerland, researchers have developed a device for rapid simultaneous detection of up to 16 different biomarkers. The device doesn’t require plasma separation, so an accompanying centrifuge is **t needed. It does require a small and inexpensive microscope to read the results. The device itself is battery powered and small e**ugh to be carried into the field.

A sample of only .005 milliliters is needed to run the various tests within the microfluidic device, which go through both an analog and digital detection systems, a major achievement of this project. The digital component is best suited for low concentrations of the analyte being looked for, while the analog part is for higher concentrations when digital signal saturation occurs.

The researchers successfully tested the device on very small samples of the anti-Ebola antibodies, demonstrating its effectiveness for diag**stic applications.

Study in ACS NA**: A Digital–Analog Microfluidic Platform for Patient-Centric Multiplexed Biomarker Diag**stics of Ultralow Volume Samples… (http://pubs.acs.org/doi/abs/10.1021/acsna**.5b07939)

EPFL:*A portable device for rapid and highly sensitive diag**stics… (http://actu.epfl.ch/news/a-portable-device-for-rapid-and-highly-sensitive-d/)

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