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08-11-2015, 10:20 PM
Elastic Material Sticks to Skin, Releases ***** When Stretched
Ahttp://www.medgadget.com/wp-content/uploads/2015/08/stretch-drug-release.png team of investigators from***rth Carolina State University and the University of **rth Carolina at Chapel Hill have designed a **vel drug release tech**logy that relies on a stretchable elastomer and drug loaded na**particles to unload medication when the skin flexes*and contracts. The idea is that this kind of approach can deliver ***** transdermally only when needed. For example, people with arthritis may be able to get pain relieving ***** during walks in doses that are proportional to how many steps are taken.
The *****es consist of an elastomer that has tiny capsules throughout its surface, each filled with drug loaded na**particles. The na**particles are designed to slowly release a medication into the capsules where they reside. The capsules themselves are **t impermeable, but will let compounds through when e**ugh pressure is applied to them. This pressure comes from stretching of the elastomer film, which in turn stretches the capsules and compresses them to release the *****. Microneedles placed below each capsule allow the ***** to pass into the skin. The combination of the mechanisms lets the*na**particles load the capsules with a small amount of a medication and release it into the skin immediately on demand.
Study in ACS Na**: Stretch-Triggered Drug Delivery from Wearable Elastomer Films Containing Therapeutic Depots… (http://pubs.acs.org/doi/abs/10.1021/acsna**.5b03975)
Via***rth Carolina State University (https://news.ncsu.edu/2015/08/tech**logy-releases-*****-when-stretched/)…
The post Elastic Material Sticks to Skin, Releases ***** When Stretched (http://www.medgadget.com/2015/08/elastic-material-sticks-skin-releases-*****-stretched.html) appeared first on Medgadget (http://www.medgadget.com).
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Ahttp://www.medgadget.com/wp-content/uploads/2015/08/stretch-drug-release.png team of investigators from***rth Carolina State University and the University of **rth Carolina at Chapel Hill have designed a **vel drug release tech**logy that relies on a stretchable elastomer and drug loaded na**particles to unload medication when the skin flexes*and contracts. The idea is that this kind of approach can deliver ***** transdermally only when needed. For example, people with arthritis may be able to get pain relieving ***** during walks in doses that are proportional to how many steps are taken.
The *****es consist of an elastomer that has tiny capsules throughout its surface, each filled with drug loaded na**particles. The na**particles are designed to slowly release a medication into the capsules where they reside. The capsules themselves are **t impermeable, but will let compounds through when e**ugh pressure is applied to them. This pressure comes from stretching of the elastomer film, which in turn stretches the capsules and compresses them to release the *****. Microneedles placed below each capsule allow the ***** to pass into the skin. The combination of the mechanisms lets the*na**particles load the capsules with a small amount of a medication and release it into the skin immediately on demand.
Study in ACS Na**: Stretch-Triggered Drug Delivery from Wearable Elastomer Films Containing Therapeutic Depots… (http://pubs.acs.org/doi/abs/10.1021/acsna**.5b03975)
Via***rth Carolina State University (https://news.ncsu.edu/2015/08/tech**logy-releases-*****-when-stretched/)…
The post Elastic Material Sticks to Skin, Releases ***** When Stretched (http://www.medgadget.com/2015/08/elastic-material-sticks-skin-releases-*****-stretched.html) appeared first on Medgadget (http://www.medgadget.com).
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