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06-18-2015, 04:11 PM
Lab-on-a-Chip Simulates Heartbeat for Testing New Drug Therapies (VIDEO)
http://cdn.medgadget.com/wp-content/uploads/2015/06/hearbeat-on-a-chip.png
http://cdn.medgadget.com/wp-content/uploads/2015/06/heartbeat-chip-diagram.pngOur hearts evolved to pump blood in a pulsing manner. The heartbeat that nearly the entire body experiences may be important for a variety of biological processes, but laboratory experiments are **rmally performed without accounting for this factor. **w researchers at the University of Michigan have developed a microfluidic chip that uses gravity and pressure differences to simulate a pulsating microenvironment within which tests can be performed.
The chip costs pennies to produce, consisting of **thing but carefully produced*lithographed silicon rubber. The device can be preloaded to be fed by a specific mix of cells, compounds, and corresponding media, and left to pump them through for hours to get a perspective of what effect pulsed rhythms have on different processes.
Here’s a U of M video with Shuichi Takayama, the lead researcher on the project:
Study in Nature Communications: Multiple independent auto**mous hydraulic oscillators driven by a common gravity head… (http://www.nature.com/ncomms/2015/150615/ncomms8301/full/ncomms8301.html)
Source: University of Michigan… (http://ns.umich.edu/new/multimedia/videos/22954-heartbeat-on-a-chip-could-improve-pharmaceutical-tests)
The post Lab-on-a-Chip Simulates Heartbeat for Testing New Drug Therapies (VIDEO) (http://www.medgadget.com/2015/06/lab-on-a-chip-simulates-heartbeat-for-testing-new-drug-therapies.html) appeared first on Medgadget (http://www.medgadget.com).
http://feeds.feedburner.com/~ff/Medgadget?d=yIl2AUoC8zA (http://feeds.feedburner.com/~ff/Medgadget?a=ZStfKumHuvA:u0Mr1S62wTQ:yIl2AUoC8zA) http://feeds.feedburner.com/~ff/Medgadget?d=qj6IDK7rITs (http://feeds.feedburner.com/~ff/Medgadget?a=ZStfKumHuvA:u0Mr1S62wTQ:qj6IDK7rITs) http://feeds.feedburner.com/~ff/Medgadget?i=ZStfKumHuvA:u0Mr1S62wTQ:gIN9vFwOqvQ (http://feeds.feedburner.com/~ff/Medgadget?a=ZStfKumHuvA:u0Mr1S62wTQ:gIN9vFwOqvQ)
http://feeds.feedburner.com/~r/Medgadget/~4/ZStfKumHuvA
http://cdn.medgadget.com/wp-content/uploads/2015/06/hearbeat-on-a-chip.png
http://cdn.medgadget.com/wp-content/uploads/2015/06/heartbeat-chip-diagram.pngOur hearts evolved to pump blood in a pulsing manner. The heartbeat that nearly the entire body experiences may be important for a variety of biological processes, but laboratory experiments are **rmally performed without accounting for this factor. **w researchers at the University of Michigan have developed a microfluidic chip that uses gravity and pressure differences to simulate a pulsating microenvironment within which tests can be performed.
The chip costs pennies to produce, consisting of **thing but carefully produced*lithographed silicon rubber. The device can be preloaded to be fed by a specific mix of cells, compounds, and corresponding media, and left to pump them through for hours to get a perspective of what effect pulsed rhythms have on different processes.
Here’s a U of M video with Shuichi Takayama, the lead researcher on the project:
Study in Nature Communications: Multiple independent auto**mous hydraulic oscillators driven by a common gravity head… (http://www.nature.com/ncomms/2015/150615/ncomms8301/full/ncomms8301.html)
Source: University of Michigan… (http://ns.umich.edu/new/multimedia/videos/22954-heartbeat-on-a-chip-could-improve-pharmaceutical-tests)
The post Lab-on-a-Chip Simulates Heartbeat for Testing New Drug Therapies (VIDEO) (http://www.medgadget.com/2015/06/lab-on-a-chip-simulates-heartbeat-for-testing-new-drug-therapies.html) appeared first on Medgadget (http://www.medgadget.com).
http://feeds.feedburner.com/~ff/Medgadget?d=yIl2AUoC8zA (http://feeds.feedburner.com/~ff/Medgadget?a=ZStfKumHuvA:u0Mr1S62wTQ:yIl2AUoC8zA) http://feeds.feedburner.com/~ff/Medgadget?d=qj6IDK7rITs (http://feeds.feedburner.com/~ff/Medgadget?a=ZStfKumHuvA:u0Mr1S62wTQ:qj6IDK7rITs) http://feeds.feedburner.com/~ff/Medgadget?i=ZStfKumHuvA:u0Mr1S62wTQ:gIN9vFwOqvQ (http://feeds.feedburner.com/~ff/Medgadget?a=ZStfKumHuvA:u0Mr1S62wTQ:gIN9vFwOqvQ)
http://feeds.feedburner.com/~r/Medgadget/~4/ZStfKumHuvA