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06-03-2015, 10:20 PM
Rice Microendoscope Hopes to Make Esophageal Biopsies Thing of Past (VIDEO)
http://cdn.medgadget.com/wp-content/uploads/2015/06/microendoscope.png
At Rice University engineers have been working on making certain biopsies unnecessary by imaging suspected tissues without excising them. The microendoscope device provides a high resolution image of tissues down to the level of individual cells, offering a view of the cellular morphology that can show signs of the presence of cancer.
http://cdn.medgadget.com/wp-content/uploads/2015/06/microendoscope-zoom.pngIn these images from Rice’s high-resolution microendoscope, the white spots are cell nuclei, which are irregularly shaped and enlarged in cancerous tumors (bottom) as compared with healthy tissue (top). –
In a study conducted in the U.S. and China of patients suspected of having*malignant squamous cell tumors, the device was used alongside a regular endoscope. Results of biopsies ordered after a traditional endoscopic imaging were compared with the results from the microendoscope. These showed that the tech**logy is capable of sparing patients unnecessary biopsies and can be used alongside traditional*Lugol’s chromoendoscopy for diag**sing esophageal squamous cell neoplasia.
Some details from the study in journal Gastroenterology:
<blockquote>In this prospective trial, 147 consecutive high-risk patients were enrolled from two US and two Chinese tertiary centers. Three expert and four **vice endoscopists performed white light endoscopy followed by LCE and HRME. All optical images were compared to gold standard of histopathology.
Using a per biopsy analysis, sensitivity of LCE vs. LCE + HRME was 96% vs. 91% (p=0.0832), specificity 48% vs. 88% (p
http://cdn.medgadget.com/wp-content/uploads/2015/06/microendoscope.png
At Rice University engineers have been working on making certain biopsies unnecessary by imaging suspected tissues without excising them. The microendoscope device provides a high resolution image of tissues down to the level of individual cells, offering a view of the cellular morphology that can show signs of the presence of cancer.
http://cdn.medgadget.com/wp-content/uploads/2015/06/microendoscope-zoom.pngIn these images from Rice’s high-resolution microendoscope, the white spots are cell nuclei, which are irregularly shaped and enlarged in cancerous tumors (bottom) as compared with healthy tissue (top). –
In a study conducted in the U.S. and China of patients suspected of having*malignant squamous cell tumors, the device was used alongside a regular endoscope. Results of biopsies ordered after a traditional endoscopic imaging were compared with the results from the microendoscope. These showed that the tech**logy is capable of sparing patients unnecessary biopsies and can be used alongside traditional*Lugol’s chromoendoscopy for diag**sing esophageal squamous cell neoplasia.
Some details from the study in journal Gastroenterology:
<blockquote>In this prospective trial, 147 consecutive high-risk patients were enrolled from two US and two Chinese tertiary centers. Three expert and four **vice endoscopists performed white light endoscopy followed by LCE and HRME. All optical images were compared to gold standard of histopathology.
Using a per biopsy analysis, sensitivity of LCE vs. LCE + HRME was 96% vs. 91% (p=0.0832), specificity 48% vs. 88% (p