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04-03-2015, 01:30 AM
Na**needles Help Build New Blood Vessels
http://www.medgadget.com/wp-content/uploads/2015/04/na**needles-for-angiogenesis.jpg
http://www.medgadget.com/wp-content/uploads/2015/04/na**needles-microscope.jpgOptical microscopy image of human cells (green) on the na**needles (orange). The na**needles have injected DNA into the cells’ nuclei (blue).
A team of scientists from*Imperial College London and Houston Methodist Research Institute have developed a new technique that*helps promote the growth of new blood vessels. This angiogenesis relies on a specially designed bed of porous na**needles loaded with nucleic acids. When cells are placed on top of this structure, the needles penetrate their membranes, delivering the nucleic acids into their nuclei, which in turn promotes rapid growth.
The silicon needles actually remain within the cells, degrading within days without a trace, save for a bit of harmless*orthosilicic acid. The team tested the new tech**logy on human cells and on living mice, delivering the nucleic acids into their back muscles. A week following treatment, the muscles that were subject to the loaded na**needles showed a six-fold increase in angiogenesis that continued to generate a**ther week later. **tably, there was ** apparent increase in inflammation or any other **ticeable side effects.
The researchers are looking at moving this tech**logy forward to help repair damaged tissues, as well as in aiding with organ transplants.
Source: Imperial College London… (http://www3.imperial.ac.uk/newsandeventspggrp/imperialcollege/newssummary/news_30-3-2015-16-4-58)
The post Na**needles Help Build New Blood Vessels (http://www.medgadget.com/2015/04/na**needles-help-build-new-blood-vessels.html) appeared first on Medgadget (http://www.medgadget.com).
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http://www.medgadget.com/wp-content/uploads/2015/04/na**needles-for-angiogenesis.jpg
http://www.medgadget.com/wp-content/uploads/2015/04/na**needles-microscope.jpgOptical microscopy image of human cells (green) on the na**needles (orange). The na**needles have injected DNA into the cells’ nuclei (blue).
A team of scientists from*Imperial College London and Houston Methodist Research Institute have developed a new technique that*helps promote the growth of new blood vessels. This angiogenesis relies on a specially designed bed of porous na**needles loaded with nucleic acids. When cells are placed on top of this structure, the needles penetrate their membranes, delivering the nucleic acids into their nuclei, which in turn promotes rapid growth.
The silicon needles actually remain within the cells, degrading within days without a trace, save for a bit of harmless*orthosilicic acid. The team tested the new tech**logy on human cells and on living mice, delivering the nucleic acids into their back muscles. A week following treatment, the muscles that were subject to the loaded na**needles showed a six-fold increase in angiogenesis that continued to generate a**ther week later. **tably, there was ** apparent increase in inflammation or any other **ticeable side effects.
The researchers are looking at moving this tech**logy forward to help repair damaged tissues, as well as in aiding with organ transplants.
Source: Imperial College London… (http://www3.imperial.ac.uk/newsandeventspggrp/imperialcollege/newssummary/news_30-3-2015-16-4-58)
The post Na**needles Help Build New Blood Vessels (http://www.medgadget.com/2015/04/na**needles-help-build-new-blood-vessels.html) appeared first on Medgadget (http://www.medgadget.com).
http://feeds.feedburner.com/~ff/Medgadget?d=yIl2AUoC8zA (http://feeds.feedburner.com/~ff/Medgadget?a=wmBOUn6r_7Y:nCiMnGdO7n4:yIl2AUoC8zA) http://feeds.feedburner.com/~ff/Medgadget?d=qj6IDK7rITs (http://feeds.feedburner.com/~ff/Medgadget?a=wmBOUn6r_7Y:nCiMnGdO7n4:qj6IDK7rITs) http://feeds.feedburner.com/~ff/Medgadget?i=wmBOUn6r_7Y:nCiMnGdO7n4:gIN9vFwOqvQ (http://feeds.feedburner.com/~ff/Medgadget?a=wmBOUn6r_7Y:nCiMnGdO7n4:gIN9vFwOqvQ)
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