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مشاهدة النسخة كاملة : Draw-On Wearable Sensors Enabled by Enzymatic Inks


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03-11-2015, 02:49 AM
Draw-On Wearable Sensors Enabled by Enzymatic Inks
Researchers from the Department of Na**Engineering at the*University of California, San Diego (http://ucsdnews.ucsd.edu/pressrelease/pens_filled_with_high_tech_inks_for_do_it_yourself _sensors)*have developed a ****** of enzyme-based inks which can be used to create a variety of low-cost, wearable, sensors for medical and environmental*applications. The inks can be easily applied using a simple ball point pen.

The researchers*sought to create a sensor that could be safe, reproducible, easy to apply and accurate in a variety of settings. To do so they used a mixture of the biocompatible binder*polyethylene glycol, conductive graphite powder, chitosan to enhance surface adhesion and the sugar substitute xylitol as a stabilising agent.*The resulting*enzymatic ink has thus been optimized for ensuring good biocatalytic activity, electrical conductivity, biocompati*bility, reproducible writing and surface adherence.*The inks*offer rapid fabrication of high-quality, flexible & inexpensive bio-sensors which can be easily applied*to a wide variety of surfaces & textures with minimal user training.

The team, led by Prof. Joseph Wang, have been working on enzyme-based sensors for lactate (http://www.medgadget.com/2013/07/lactate-sensing-temporary-tattoo-to-help-athletes-perform-at-anaerobic-peak.html) and glucose (http://www.medgadget.com/2015/01/printed-tattoo-glucose-sensor-takes-on-hated-pinpricks.html) sensing for several years, and their current delivery system seems to*be an evolution of the **n-invasive*wearable tattoo glucose sensor (http://www.medgadget.com/2015/01/printed-tattoo-glucose-sensor-takes-on-hated-pinpricks.html)we covered early last year.*The researchers have showcased*two applications of their enzymatic ink-based roller pens in the latest issue of the journal Advanced Healthcare Materials (http://onlinelibrary.wiley.com/doi/10.1002/adhm.201400808/abstract;jsessionid=B2B01B324CCBD3D75D274D5E32F3E1 B7.f01t02): epidermal*blood-glucose sensing*and detection*of carbolic acid on a leaf as shown in the video (https://hameed.nwar.uk/vb/The%20biggest challenge the researchers faced was making inks from chemicals and biochemicals that aren’t harmful to humans or plants; could function as the sensors’ electrodes; and retain their properties over long periods in storage and in various conditions.).

The team estimates that a single pen of ink can be used to draw the equivalent of 500 glucometer test strips. With the proliferation of wearable tech**logies, solutions like this which can produce, conformable, low cost, robust sensors for on-skin monitoring may have huge implications for how diseases are monitored and managed in the future.



Press Release* (http://ucsdnews.ucsd.edu/pressrelease/pens_filled_with_high_tech_inks_for_do_it_yourself _sensors)

Video (http://ucsdnews.ucsd.edu/news_uploads/joe-wang-pens-3-arm.jpg)

Image (http://ucsdnews.ucsd.edu/news_uploads/joe-wang-pens-3-arm.jpg)

Advanced Healthcare Materials Article (http://onlinelibrary.wiley.com/doi/10.1002/adhm.201400808/abstract;jsessionid=B2B01B324CCBD3D75D274D5E32F3E1 B7.f01t02)









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