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02-05-2015, 03:18 AM
ELISA Immu**assay Disease Testing on Your Smartphone
http://www.medgadget.com/wp-content/uploads/2015/02/9933.jpg
Though ELISA tests (enzyme-linked immu**sorbent assays) are the gold standard for diag**sing a whole slew of infectious diseases, the tech**logy has remained stuck within hospital labs. What if you could carry*an ELISA machine with you in your pocket? Imagine field testing for diseases, halting their spread and initiating therapy at an early stage for those infected. Researchers at Columbia University have actually developed such a device that works in conjunction with a smartphone to provide results within minutes.
http://www.medgadget.com/wp-content/uploads/2015/02/smartphone-sensor-device.jpgThe device uses the smartphone as the power source and performs a triplexed immu**assay for HIV antibody,*treponemal-specific antibody for syphilis, and **n-treponemal antibody for active syphilis infection. Such a combination immu**assay has **t been previously available in a unified test.
It has already been trialed in field tests in Rwanda on 96 people enrolled in disease transmission prevention programs and volunteers in counseling and testing centers. The device will cost roughly $34 to manufacture, orders of magnitude cheaper than conventional ELISA machines while providing similar*accuracy of results.
From the study in Science Translational Medicine:
In a blinded experiment, health care workers obtained diag**stic results in 15 min from our triplex test that rivaled the gold standard of laboratory-based HIV ELISA and rapid plasma reagin (a screening test for syphilis), with sensitivity of 92 to 100% and specificity of 79 to 100%, consistent with needs of current clinical algorithms. Patient preference for the dongle was 97% compared to laboratory-based tests, with most pointing to the convenience of obtaining quick results with a single fingerprick. This work suggests that coupling microfluidics with recent advances in consumer electronics can make certain laboratory-based diag**stics accessible to almost any population with access to smartphones.
Study in Science Translational Medicine: A smartphone dongle for diag**sis of infectious diseases at the point of care… (http://stm.sciencemag.org/content/7/273/273re1.abstract?sid=a8091f23-cfae-4b8a-aea2-e7a44a4a4a7e)
More: Smartphone, Finger Prick, 15 Minutes, Diag**sis—Done! (http://engineering.columbia.edu/smartphone-finger-prick-15-minutes-diag**sis%E2%80%94done-0)
The post ELISA Immu**assay Disease Testing on Your Smartphone (http://www.medgadget.com/2015/02/elisa-immu**assay-disease-testing-on-your-smartphone.html) appeared first on Medgadget (http://www.medgadget.com).
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http://www.medgadget.com/wp-content/uploads/2015/02/9933.jpg
Though ELISA tests (enzyme-linked immu**sorbent assays) are the gold standard for diag**sing a whole slew of infectious diseases, the tech**logy has remained stuck within hospital labs. What if you could carry*an ELISA machine with you in your pocket? Imagine field testing for diseases, halting their spread and initiating therapy at an early stage for those infected. Researchers at Columbia University have actually developed such a device that works in conjunction with a smartphone to provide results within minutes.
http://www.medgadget.com/wp-content/uploads/2015/02/smartphone-sensor-device.jpgThe device uses the smartphone as the power source and performs a triplexed immu**assay for HIV antibody,*treponemal-specific antibody for syphilis, and **n-treponemal antibody for active syphilis infection. Such a combination immu**assay has **t been previously available in a unified test.
It has already been trialed in field tests in Rwanda on 96 people enrolled in disease transmission prevention programs and volunteers in counseling and testing centers. The device will cost roughly $34 to manufacture, orders of magnitude cheaper than conventional ELISA machines while providing similar*accuracy of results.
From the study in Science Translational Medicine:
In a blinded experiment, health care workers obtained diag**stic results in 15 min from our triplex test that rivaled the gold standard of laboratory-based HIV ELISA and rapid plasma reagin (a screening test for syphilis), with sensitivity of 92 to 100% and specificity of 79 to 100%, consistent with needs of current clinical algorithms. Patient preference for the dongle was 97% compared to laboratory-based tests, with most pointing to the convenience of obtaining quick results with a single fingerprick. This work suggests that coupling microfluidics with recent advances in consumer electronics can make certain laboratory-based diag**stics accessible to almost any population with access to smartphones.
Study in Science Translational Medicine: A smartphone dongle for diag**sis of infectious diseases at the point of care… (http://stm.sciencemag.org/content/7/273/273re1.abstract?sid=a8091f23-cfae-4b8a-aea2-e7a44a4a4a7e)
More: Smartphone, Finger Prick, 15 Minutes, Diag**sis—Done! (http://engineering.columbia.edu/smartphone-finger-prick-15-minutes-diag**sis%E2%80%94done-0)
The post ELISA Immu**assay Disease Testing on Your Smartphone (http://www.medgadget.com/2015/02/elisa-immu**assay-disease-testing-on-your-smartphone.html) appeared first on Medgadget (http://www.medgadget.com).
http://feeds.feedburner.com/~ff/Medgadget?d=yIl2AUoC8zA (http://feeds.feedburner.com/~ff/Medgadget?a=5ewFUynVTcA:GxDWa5JE1D4:yIl2AUoC8zA) http://feeds.feedburner.com/~ff/Medgadget?d=qj6IDK7rITs (http://feeds.feedburner.com/~ff/Medgadget?a=5ewFUynVTcA:GxDWa5JE1D4:qj6IDK7rITs) http://feeds.feedburner.com/~ff/Medgadget?i=5ewFUynVTcA:GxDWa5JE1D4:gIN9vFwOqvQ (http://feeds.feedburner.com/~ff/Medgadget?a=5ewFUynVTcA:GxDWa5JE1D4:gIN9vFwOqvQ)
https://hameed.nwar.uk/vb//feeds.feedburner.com/~r/Medgadget/~4/5ewFUynVTcA